What is the ultimate act of generosity? According to filmmaker Penny Lane, the answer to that question is "donating your kidney to a complete stranger without expecting anything in return". In Confessions of a Good Samaritan, Penny Lane takes us on a quest for the purest form of altruism. Her mission to become a true Samaritan turns out to be a provocative examination of the science, history and ethics of organ transplants. She sheds new light on the age-old question, "Who is your neighbor and what do we owe him/her?".